Opioids Market to 2018 - Increasing Concentration of
Abuse-Resistant Branded Generics Alter Competitive Dynamics in this Flat
Market
Summary
Leading business intelligence provider GBI Research has released
its latest research report, entitled “Opioids Market to 2018 -
Increasing Concentration of Abuse-Resistant Branded Generics Alter
Competitive Dynamics in this Flat Market”. The current opioids market is
characterized by a very broad and highly diversified product portfolio.
Patients experiencing moderate to severe pain for a range of underlying
physiological reasons are virtually exclusively treated with opioid
analgesics. As a result, most patient populations experiencing more
severe levels of pain across most pain indications, with the exception
of, for example, migraines, are heavily dominated by opioids. As a
therapeutic drug class, opioids have virtually no competition from
molecules with non-opioid receptor targets. However, although the
competition is virtually exclusively limited to opioid compounds, the
current environment within this therapeutic class is highly competitive
and strongly diversified. The approved drugs are based on 16 different
opioid compounds and are differentiated on a range of characteristics,
which include dosage, route of administration and pharmacokinetic
features, as well as increasingly on the basis of abuse-resistance
technologies.
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Whilst the prescription rates of opioid analgesic have seen a
historically unprecedented increase over the last two decades,
particularly in the US, this has resulted in a dramatic concomitant
increase in opioid abuse and dependency. Over the last few years, the
growing concern over opioid abuse has resulted in tighter regulations
and increasingly vocal concerns by physicians. Due to these concerns
from regulatory authorities and physicians about growing opioid abuse,
there has been a seismic shift towards developing abuse-resistant
formulations of extended-release opioid analgesics, including both novel
products and reformulations of existing ones. Since the launch of the
first abuse-resistant product, Embeda, in 2009, a whole range of novel
products and reformulations of existing product ranges have been brought
to the market. While abuse-resistant formulations do not confer any
clinical benefits, they have become an essential differentiating factor
in the current market environment in order ensure that products remain
competitive for the future. There is a growing concentration and
competition among abuse-resistant products, which is expected to be the
primary driving factor in this largely stagnant market, particularly as
the current developmental pipeline is very small and is characterized by
a lack of innovation, with virtually no novel compounds and strong
saturation across multiple pain indications.
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Scope
- An overview of the current opioid product market.
- A brief discussion about the inconsistent prescription preferences among European physicians.
- A brief profile of the most important opioid products.
- A pipeline analysis of the opioid products currently in development and an overview of the developmental pipeline by phase, by the route of administration and a summary of the promising pipeline products.
- An overview of the M&A and licensing deals, as well as co-development deals, across multiple indications in which opioids are frequently used in patients suffering from moderate to severe pain.
Reasons to buy
- Identify trends in the developmental pipeline for opioid analgesics.
- Develop their awareness of the regulatory environment, physician concerns and inconsistency of prescription preferences among physicians.
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